Case Number : Case 1861 - 16 July - Dr Limin Yu Posted By: Guest

Suprbasal acantholysis extending into a hair follicle, nice tombstone appearance, Pemphigus vulgaris

Amazing :-)

Great case of PV!

Agree with above. Nice follicular extension of acantholisis. 

Pemphigus vulgaris with an unbelievable suprabasilar acantholysis extending deep down to the follicular infundibulum.

Agree with the pattern description of the colleagues, probable PV to confirm with immunofluorescence

Pattern is very suggestive of PV "textbook example", correlation with DIF finding +/- ELISAs for DSG1/DSG3 is essential to firm up such diagnosis including evidence of mucosal involvement (though the latter can rarely be spared in PV).

This is a PV!  Thank everyone for the discussion. The patient did have mucosal involvement. DIF was performed at an outside institute. I will update its results once it's available to me. 

DIF showed intercellular deposit of IgG and C3 in the epithelium of the lip, confirmatory of PV. Thanks!