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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 1244 - 31 March Posted By: Guest

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40 year old woman with a 5 mm papule on the vulva.

Case posted by Dr Uma Sundram


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Guest Romualdo

Posted

Mammary-like gland adenoma of the vulva, in this particular case resembling sclerosing adenosis.

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Dr. Mona Abdel-Halim

Posted

Isn't mammary-like-gland adenoma of the vulva equivalent to hidradenoma papilliferum?
I thought of this lesion as tubular apocrine adenoma, as I did not perceive the typical architecture of hidradenoma papilliferum.

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Guest Romualdo

Posted

Mona, mammary-like gland adenoma of the vulva is not completely equivalent to hidradenoma papilliferum. Tumors resembling breast lesions such as erosive adenomatosis, sclerosing adenosis, ductal adenoma, papillary adenofibroma, etc, are now considered variants of mammary-like gland adenoma. I think this case resembles sclerosing adenosis.

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Agree. Mammary-like gland adenoma of vulva.

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Guest Jim Davie MD

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Agree with Romualdo. Mammary-like gland adenoma of vulva. [/size][/font][/color]

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]That said, I can see argument for being a "lumper" for the clinician's sake, and classifying these as a hidradenoma variant (HP or tubulopapillary hidradenoma) if histology is not clear-cut, e.g. no [/size][/font][/color][color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]mammary-like glands (MLG) in adjacent tissue.[/size][/font][/color]

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Some structures resemble mammary ducts. There is double-layer with apocrine type secretion. There may be some patchy absence of myoepithelial layer in some of the sclerotic glands but that would not be of concern for a sclerosing adenosis-like lesion.[/size][/font][/color]

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Uma Sundram

Posted

Mammary like gland adenoma of the vulva.

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